Biomarkers

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Erythropoietin - Biomarker

Results for "Erythropoietin"

Target: Erythropoietin

Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass (PubMed:28283061). Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3 (PubMed:9774108)

Clinical Applications

NormalPolycythemiaAnemiaPolycythemia VeraChronic Kidney Disease

uniprot

Approved Therapies

PROCRIT (ERYTHROPOIETIN) ^[5]

Status: approved

APPROVED

EPOGEN (EPOETIN ALFA) ^[6]

Status: approved

APPROVED

RETACRIT (EPOETIN ALFA-EPBX) ^[7]

Status: approved

APPROVED

RETACRIT (EPOETIN ALFA-EPBX) ^[8]

Status: approved

APPROVED

Pipeline Therapies

Canakinumab With Darbepoetin Alfa in PTs With Lower-Risk MDS Who Have Failed ESA

H. Lee Moffitt Cancer Center and Research Institute

PHASE1, PHASE2

Identifying Biological Markers for Altitude Exposure and Use of Recombinant Human Erythropoietin (rHuEPO)

University of Copenhagen

Effect of Recombinant Human EPO on the Postoperative Neurologic Outcome in Pediatric Moyamoya Patients

Seoul National University Hospital

Front Line Ibrutinib Without Corticosteroids for Newly Diagnosed Chronic Graft-versus-Host Disease

National Institutes of Health Clinical Center (CC)

PHASE2

A Phase 1, Dose-Escalation Trial of PT2385 Tablets In Patients With Advanced Clear Cell Renal Cell Carcinoma (MK-3795-001)

Peloton Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

PHASE1

Companies Working on Erythropoietin

H. Lee Moffitt Cancer Center and Research Institute

Myelodysplastic Syndromes

Darbepoetin alfa

University of Copenhagen

Healthy

Seoul National University Hospital

Moyamoya Disease

Epoetin Alfa

National Institutes of Health Clinical Center (CC)

Chronic GVHD

AzithromycinVoriconazolePosaconazole

TrialsMap

Clinical Intelligence Agent

Interactive Clinical Trials Map

349

Europe

199

United States

151

Asia

101

Other

LitSearch

Scientific Literature Agent

Scientific Publications

Recombinant erythropoietin.

PubMedNone 1993

[Non-hematogenic activity of erythropoietin].

PubMedNone 2019

Erythropoietin and erythropoiesis.

PubMedSep 2009

Erythropoietin in obstetrics.

PubMedAug 1998

Erythropoietin regulates signaling pathways associated with neuroprotective events.

PubMedMay 2022

Research Insights

Publication count:

5 papers

Research focus:

Normal

Sources & References

Recombinant erythropoietin.

PubMed•None 1993

[Non-hematogenic activity of erythropoietin].

PubMed•None 2019

Erythropoietin and erythropoiesis.

PubMed•Sep 2009

Erythropoietin in obstetrics.

PubMed•Aug 1998

Erythropoietin regulates signaling pathways associated with neuroprotective events.

PubMed•May 2022

Biomarkers

Results for "Erythropoietin"

Target: Erythropoietin

Clinical Applications

Approved Therapies

PROCRIT (ERYTHROPOIETIN) [5]

EPOGEN (EPOETIN ALFA) [6]

RETACRIT (EPOETIN ALFA-EPBX) [7]

RETACRIT (EPOETIN ALFA-EPBX) [8]

Pipeline Therapies

Canakinumab With Darbepoetin Alfa in PTs With Lower-Risk MDS Who Have Failed ESA

Identifying Biological Markers for Altitude Exposure and Use of Recombinant Human Erythropoietin (rHuEPO)

Effect of Recombinant Human EPO on the Postoperative Neurologic Outcome in Pediatric Moyamoya Patients

Front Line Ibrutinib Without Corticosteroids for Newly Diagnosed Chronic Graft-versus-Host Disease

A Phase 1, Dose-Escalation Trial of PT2385 Tablets In Patients With Advanced Clear Cell Renal Cell Carcinoma (MK-3795-001)

Companies Working on Erythropoietin

H. Lee Moffitt Cancer Center and Research Institute

University of Copenhagen

Seoul National University Hospital

National Institutes of Health Clinical Center (CC)

TrialsMap

Interactive Clinical Trials Map

LitSearch

Scientific Publications

Recombinant erythropoietin.

[Non-hematogenic activity of erythropoietin].

Erythropoietin and erythropoiesis.

Erythropoietin in obstetrics.

Erythropoietin regulates signaling pathways associated with neuroprotective events.

Research Insights

Sources & References

PROCRIT (ERYTHROPOIETIN) ^[5]

EPOGEN (EPOETIN ALFA) ^[6]

RETACRIT (EPOETIN ALFA-EPBX) ^[7]

RETACRIT (EPOETIN ALFA-EPBX) ^[8]