Biomarkers

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Results for "Pro-glucagon"

Target: Pro-glucagon

Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes

Clinical Applications

Normal

uniprot

Approved Therapies

TRULICITY (DULAGLUTIDE) ^[5]

Status: approved

APPROVED

Liraglutide (LIRAGLUTIDE) ^[6]

Status: approved

APPROVED

Liraglutide (LIRAGLUTIDE) ^[7]

Status: approved

APPROVED

Liraglutide (LIRAGLUTIDE) ^[8]

Status: approved

APPROVED

Glucagon (GLUCAGON) ^[9]

Status: approved

APPROVED

Victoza (LIRAGLUTIDE) ^[10]

Status: approved

APPROVED

Pipeline Therapies

Comparison of Low, Moderate and High Carbohydrate Diet on Insulin Requirements and Metabolic Control in Type 1 Diabetes

Karolinska Institutet

Identifying Strategies to Curtail Weight Regain After GLP-1 Receptor Agonist Treatment Cessation

University of Texas Southwestern Medical Center

Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome.

VectivBio AG

PHASE3

Nationwide Utilization of Danish Government Electronic Letter System for Increasing Guideline-directed Medical Therapy in Chronic Kidney Disease

Herlev and Gentofte Hospital

Dose-Finding Study Evaluating Effect on Body Composition of Enobosarm in Patients Taking a GLP-1 for Chronic Weight Mgmt

Veru Inc.

PHASE2

Companies Working on Pro-glucagon

Karolinska Institutet

Type1diabetes

University of Texas Southwestern Medical Center

Obesity

VectivBio AG

Short Bowel Syndrome

Herlev and Gentofte Hospital

Chronic Kidney Diseases

TrialsMap

Clinical Intelligence Agent

Interactive Clinical Trials Map

548

United States

414

Europe

225

Asia

109

Other

LitSearch

Scientific Literature Agent

Scientific Publications

Glucagon and regulation of glucose metabolism.

PubMedApr 2003

Glucagon Receptor Signaling and Glucagon Resistance.

PubMedJul 2019

Role of Glucagon and Its Receptor in the Pathogenesis of Diabetes.

PubMedNone 2022

100 years of glucagon and 100 more.

PubMedAug 2023

Hepatic glucagon action: beyond glucose mobilization.

PubMedJul 2024

Research Insights

Publication count:

5 papers

Research focus:

Normal

Sources & References

Glucagon and regulation of glucose metabolism.

PubMed•Apr 2003

Glucagon Receptor Signaling and Glucagon Resistance.

PubMed•Jul 2019

Role of Glucagon and Its Receptor in the Pathogenesis of Diabetes.

PubMed•None 2022

100 years of glucagon and 100 more.

PubMed•Aug 2023

Hepatic glucagon action: beyond glucose mobilization.

PubMed•Jul 2024

Glucagon - Biomarker

Biomarkers

Results for "Pro-glucagon"

Target: Pro-glucagon

Clinical Applications

Approved Therapies

TRULICITY (DULAGLUTIDE) [5]

Liraglutide (LIRAGLUTIDE) [6]

Liraglutide (LIRAGLUTIDE) [7]

Liraglutide (LIRAGLUTIDE) [8]

Glucagon (GLUCAGON) [9]

Victoza (LIRAGLUTIDE) [10]

Pipeline Therapies

Comparison of Low, Moderate and High Carbohydrate Diet on Insulin Requirements and Metabolic Control in Type 1 Diabetes

Identifying Strategies to Curtail Weight Regain After GLP-1 Receptor Agonist Treatment Cessation

Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome.

Nationwide Utilization of Danish Government Electronic Letter System for Increasing Guideline-directed Medical Therapy in Chronic Kidney Disease

Dose-Finding Study Evaluating Effect on Body Composition of Enobosarm in Patients Taking a GLP-1 for Chronic Weight Mgmt

Companies Working on Pro-glucagon

Karolinska Institutet

University of Texas Southwestern Medical Center

VectivBio AG

Herlev and Gentofte Hospital

TrialsMap

Interactive Clinical Trials Map

LitSearch

Scientific Publications

Glucagon and regulation of glucose metabolism.

Glucagon Receptor Signaling and Glucagon Resistance.

Role of Glucagon and Its Receptor in the Pathogenesis of Diabetes.

100 years of glucagon and 100 more.

Hepatic glucagon action: beyond glucose mobilization.

Research Insights

Sources & References

TRULICITY (DULAGLUTIDE) ^[5]

Liraglutide (LIRAGLUTIDE) ^[6]

Liraglutide (LIRAGLUTIDE) ^[7]

Liraglutide (LIRAGLUTIDE) ^[8]

Glucagon (GLUCAGON) ^[9]

Victoza (LIRAGLUTIDE) ^[10]