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Results for "Renin"

Target: Renin

Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney

Clinical Applications

HypertensionNormalPrimary hyperaldosteronismSecondary hyperaldosteronism

uniprot

Approved Therapies

Tekturna (ALISKIREN HEMIFUMARATE) ^[5]

Status: approved

APPROVED

Aliskiren (ALISKIREN HEMIFUMARATE) ^[6]

Status: approved

APPROVED

Pipeline Therapies

Nationwide Utilization of Danish Government Electronic Letter System for Increasing Guideline-directed Medical Therapy in Chronic Kidney Disease

Herlev and Gentofte Hospital

HELP-HY: Health Education and sLeep Program in HYpertension

Mayo Clinic

Heart Failure With Reduced Ejection Fraction: Adjuvant Therapy With Neurostimulation and Chlorella Pyrenoidosa (HD-tDCS)

Federal University of Paraíba

The African-PREDICT Study

North-West University, South Africa

PIPELINE

Vascular Reparative Mechanism in Diabetes

University of Alabama at Birmingham

PIPELINE

Companies Working on Renin

Herlev and Gentofte Hospital

Chronic Kidney Diseases

Mayo Clinic

Prehypertension

Federal University of Paraíba

Heart Failure

North-West University, South Africa

Cardiovascular Diseases

TrialsMap

Clinical Intelligence Agent

Interactive Clinical Trials Map

597

Europe

176

Asia

Oceania

189

Other

LitSearch

Scientific Literature Agent

Scientific Publications

Flexible and multifaceted: the plasticity of renin-expressing cells.

PubMedAug 2022

Renin Cells, From Vascular Development to Blood Pressure Sensing.

PubMedAug 2023

Physiology of kidney renin.

PubMedApr 2010

Renin and renin blockade have no role in complement activity.

PubMedFeb 2024

Control of renin synthesis and secretion.

PubMedAug 2012

Research Insights

Publication count:

5 papers

Research focus:

Hypertension

Sources & References

Flexible and multifaceted: the plasticity of renin-expressing cells.

PubMed•Aug 2022

Renin Cells, From Vascular Development to Blood Pressure Sensing.

PubMed•Aug 2023

Physiology of kidney renin.

PubMed•Apr 2010

Renin and renin blockade have no role in complement activity.

PubMed•Feb 2024

Control of renin synthesis and secretion.

PubMed•Aug 2012

Renin - Biomarker

Biomarkers

Results for "Renin"

Target: Renin

Clinical Applications

Approved Therapies

Tekturna (ALISKIREN HEMIFUMARATE) [5]

Aliskiren (ALISKIREN HEMIFUMARATE) [6]

Pipeline Therapies

Nationwide Utilization of Danish Government Electronic Letter System for Increasing Guideline-directed Medical Therapy in Chronic Kidney Disease

HELP-HY: Health Education and sLeep Program in HYpertension

Heart Failure With Reduced Ejection Fraction: Adjuvant Therapy With Neurostimulation and Chlorella Pyrenoidosa (HD-tDCS)

The African-PREDICT Study

Vascular Reparative Mechanism in Diabetes

Companies Working on Renin

Herlev and Gentofte Hospital

Mayo Clinic

Federal University of Paraíba

North-West University, South Africa

TrialsMap

Interactive Clinical Trials Map

LitSearch

Scientific Publications

Flexible and multifaceted: the plasticity of renin-expressing cells.

Renin Cells, From Vascular Development to Blood Pressure Sensing.

Physiology of kidney renin.

Renin and renin blockade have no role in complement activity.

Control of renin synthesis and secretion.

Research Insights

Sources & References

Tekturna (ALISKIREN HEMIFUMARATE) ^[5]

Aliskiren (ALISKIREN HEMIFUMARATE) ^[6]