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Results for "Transthyretin"

Target: Transthyretin

Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain

Clinical Applications

Chronic Kidney DiseaseNormalMalnutrition

uniprot

Approved Therapies

Vyndaqel (TAFAMIDIS MEGLUMINE) ^[5]

Status: approved

APPROVED

Tegsedi (INOTERSEN) ^[6]

Status: approved

APPROVED

AMVUTTRA (VUTRISIRAN) ^[7]

Status: approved

APPROVED

Attruby (ACORAMIDIS HYDROCHLORIDE) ^[8]

Status: approved

APPROVED

WAINUA (EPLONTERSEN) ^[9]

Status: approved

APPROVED

Onpattro (PATISIRAN) ^[10]

Status: approved

APPROVED

Pipeline Therapies

Open-Label Safety Study of Acoramidis (AG10) in Symptomatic ATTR Participants

Eidos Therapeutics, a BridgeBio company

PHASE3

Evaluation of an Adapted Physical Activity Program in Patients With Unresectable Pancreatic Cancer

GERCOR - Multidisciplinary Oncology Cooperative Group

Time-restricted Enteral Nutrition Versus Continuous Enteral Nutrition in Patients With Severe Stroke

First Affiliated Hospital of Wannan Medical College

CARDIO-TTRansform Magnetic Resonance Imaging (MRI) Sub-study

Ionis Pharmaceuticals, Inc.

PIPELINE

International Alfapump Cohort Study

Sequana Medical N.V.

PIPELINE

Companies Working on Transthyretin

Eidos Therapeutics, a BridgeBio company

Amyloid Cardiomyopathy

GERCOR - Multidisciplinary Oncology Cooperative Group

Unresectable Locally Advanced Cancer

First Affiliated Hospital of Wannan Medical College

Stroke

Ionis Pharmaceuticals, Inc.

Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

TrialsMap

Clinical Intelligence Agent

Interactive Clinical Trials Map

275

Europe

154

United States

138

Asia

Other

LitSearch

Scientific Literature Agent

Scientific Publications

Guideline of transthyretin-related hereditary amyloidosis for clinicians.

PubMedFeb 2013

Safety and efficacy of RNAi therapy for transthyretin amyloidosis.

PubMedAug 2013

Transthyretin Cardiac Amyloidosis.

PubMedAug 2017

Genotype and Phenotype of Transthyretin Cardiac Amyloidosis: THAOS (Transthyretin Amyloid Outcome Survey).

PubMedJul 2016

Research Insights

Publication count:

4 papers

Research focus:

Chronic Kidney Disease

Sources & References

Guideline of transthyretin-related hereditary amyloidosis for clinicians.

PubMed•Feb 2013

Safety and efficacy of RNAi therapy for transthyretin amyloidosis.

PubMed•Aug 2013

Transthyretin Cardiac Amyloidosis.

PubMed•Aug 2017

Genotype and Phenotype of Transthyretin Cardiac Amyloidosis: THAOS (Transthyretin Amyloid Outcome Survey).

PubMed•Jul 2016

Transthyretin - Biomarker

Biomarkers

Results for "Transthyretin"

Target: Transthyretin

Clinical Applications

Approved Therapies

Vyndaqel (TAFAMIDIS MEGLUMINE) [5]

Tegsedi (INOTERSEN) [6]

AMVUTTRA (VUTRISIRAN) [7]

Attruby (ACORAMIDIS HYDROCHLORIDE) [8]

WAINUA (EPLONTERSEN) [9]

Onpattro (PATISIRAN) [10]

Pipeline Therapies

Open-Label Safety Study of Acoramidis (AG10) in Symptomatic ATTR Participants

Evaluation of an Adapted Physical Activity Program in Patients With Unresectable Pancreatic Cancer

Time-restricted Enteral Nutrition Versus Continuous Enteral Nutrition in Patients With Severe Stroke

CARDIO-TTRansform Magnetic Resonance Imaging (MRI) Sub-study

International Alfapump Cohort Study

Companies Working on Transthyretin

Eidos Therapeutics, a BridgeBio company

GERCOR - Multidisciplinary Oncology Cooperative Group

First Affiliated Hospital of Wannan Medical College

Ionis Pharmaceuticals, Inc.

TrialsMap

Interactive Clinical Trials Map

LitSearch

Scientific Publications

Guideline of transthyretin-related hereditary amyloidosis for clinicians.

Safety and efficacy of RNAi therapy for transthyretin amyloidosis.

Transthyretin Cardiac Amyloidosis.

Genotype and Phenotype of Transthyretin Cardiac Amyloidosis: THAOS (Transthyretin Amyloid Outcome Survey).

Research Insights

Sources & References

Vyndaqel (TAFAMIDIS MEGLUMINE) ^[5]

Tegsedi (INOTERSEN) ^[6]

AMVUTTRA (VUTRISIRAN) ^[7]

Attruby (ACORAMIDIS HYDROCHLORIDE) ^[8]

WAINUA (EPLONTERSEN) ^[9]

Onpattro (PATISIRAN) ^[10]