This segment focuses on the development, manufacturing, and commercialization of injectable bioceramic bone graft substitutes, primarily CERAMENT products. CERAMENT Bone Void Filler, CERAMENT G, and CERAMENT V are key products, offering solutions for bone defects in various orthopedic and trauma applications. Research and development activities include continuous improvement of existing products and the development of new formulations and delivery systems. The segment leverages advanced biomaterial technologies, including hydroxyapatite and calcium sulfate, to promote bone regeneration. Patient impact is significant, as these products aid in faster healing and improved outcomes for patients with bone voids. Market positioning is strong, with a focus on providing innovative solutions in the orthobiologics market. Future opportunities include expansion into new therapeutic areas and geographic markets. Regulatory and clinical aspects are crucial, with ongoing clinical trials and regulatory submissions to ensure product safety and efficacy. Partnerships with medical professionals and institutions are essential for market access and product adoption.

This segment encompasses the company's research and development efforts, focusing on creating innovative solutions for bone healing and regeneration. The R&D activities include preclinical studies, clinical trials, and product development across various therapeutic areas, including trauma, revision arthroplasty, chronic osteomyelitis, and oncology. The company utilizes advanced biomaterials and medical technology to develop new products and improve existing ones. Technologies and methodologies include the use of injectable bioceramics, growth factors, and other regenerative medicine approaches. The therapeutic areas covered include a wide range of bone disorders and injuries. The patient impact is significant, as the research aims to improve patient outcomes and quality of life. Market positioning is based on innovation and the development of unique solutions. Future opportunities include expanding the product pipeline and entering new markets. Regulatory and clinical aspects are critical, with the need for clinical trials and regulatory approvals. Partnerships and collaborations with research institutions and medical professionals are essential for advancing the company's research goals.