Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Asacol, Pentasa, Rowasa, Lialda, Apriso, Delzicol, Mezavant, Canasa
5-ASA (5-aminosalicylic acid), also known as mesalamine, is a medication primarily used to treat inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. It belongs to the aminosalicylate class of drugs and works by reducing inflammation in the lining of the gut. While the exact mechanism is not fully understood, it is thought to involve inhibition of inflammatory mediators like leukotrienes and cytokines. It's available in various formulations designed to target different areas of the gastrointestinal tract.
For treating inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease.
Outcome:
Increased risk of myelosuppression
Mechanism:
Additive bone marrow suppression
Outcome:
Reduced efficacy of 5-ASA
Mechanism:
May interfere with 5-ASA's anti-inflammatory effects.
Outcome:
Slight decrease in 5-ASA absorption
Mechanism:
Changes in stomach pH may affect dissolution.
Most likely new formulation: Targeted release to specific intestinal segments (2025, 80% confidence)
Based on current usage trends and ongoing research, there is a 70% likelihood of new 5-ASA formulations with improved delivery systems being approved within the next 5 years.
Aminosalicylate, Anti-inflammatory
Aminosalicylate