Medicines
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Discover all available medicines and treatments
Brand: Zovirax, Sitavig, Xerese
Acyclovir is a synthetic purine nucleoside analogue antiviral drug primarily used to treat herpes simplex virus (HSV) infections, including genital herpes, chickenpox, shingles, and herpes simplex encephalitis. It works by inhibiting viral DNA replication. Acyclovir is generally well-tolerated but may cause some side effects like nausea, headache, and diarrhea. It is available in various formulations, including oral, topical, and intravenous.
For treating herpes simplex virus (HSV) infections, varicella-zoster virus (VZV) infections, and sometimes Epstein-Barr virus (EBV) infections.
Outcome:
Increased acyclovir blood levels
Mechanism:
Reduced renal clearance of acyclovir
Outcome:
Slight increase in acyclovir levels
Mechanism:
Minor inhibition of renal clearance
Outcome:
May slightly delay absorption
Mechanism:
Delayed gastric emptying
Most likely new formulation: Topical microemulsion for enhanced delivery (Year: 2026, 70% confidence)
Based on current usage patterns and emerging resistance data, there is a 15% likelihood of new guidelines for acyclovir use in specific patient populations within the next 5 years.
Antiviral, Nucleoside Analogue
Purine Nucleoside Analogue