Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Zyloprim, Aloprim, Progout
Allopurinol is a xanthine oxidase inhibitor used to treat hyperuricemia, which is a buildup of uric acid in the blood. High uric acid levels can lead to gout, kidney stones, and other medical conditions. Allopurinol works by reducing the production of uric acid. It belongs to the class of drugs known as anti-gout medications.
For the treatment of gout, kidney stones caused by high uric acid levels, and conditions that cause high uric acid levels (like certain cancers).
Outcome:
Increased risk of azathioprine toxicity (e.g., bone marrow suppression)
Mechanism:
Allopurinol inhibits the metabolism of azathioprine.
Outcome:
Increased risk of allopurinol hypersensitivity
Mechanism:
Unknown
Outcome:
Slightly increased risk of skin rash
Mechanism:
Unknown
Most likely new formulation: extended-release allopurinol for improved patient compliance (Year: 2025, 70% confidence)
Based on historical usage patterns and current research trends, there is a low ( <5%) likelihood of any major regulatory changes for allopurinol in the next 2 years.
Xanthine Oxidase Inhibitor, Antigout Agent
Purine Analogue