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Discover all available medicines and treatments
Brand: Loceryl, Curanail, Omicur
Amorolfine is a synthetic antifungal agent belonging to the morpholine class. It inhibits the biosynthesis of ergosterol, a crucial component of fungal cell membranes, by interfering with two enzymes, delta 14-reductase and delta 7-8 isomerase. This disruption leads to changes in membrane permeability and ultimately fungal cell death. Amorolfine is primarily used topically for the treatment of fungal nail infections (onychomycosis).
For the topical treatment of fungal nail infections (onychomycosis).
Outcome:
None reported
Mechanism:
Unknown
Outcome:
None reported
Mechanism:
Unknown
Outcome:
None reported
Mechanism:
Unknown
Most likely new formulation: Potential development of a combination therapy with other antifungals (Year: 2026, 30% confidence)
Based on current usage trends and clinical trial data, there is a low likelihood of significant regulatory changes for amorolfine in the near future (less than 5% chance within the next 2 years).
Antifungal
Morpholine