Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Arimidex, Anastrozol, Armidex
Anastrozole is a non-steroidal aromatase inhibitor used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It works by blocking the enzyme aromatase, which is responsible for converting androgens to estrogens in the body. By reducing estrogen levels, anastrozole helps to slow or stop the growth of breast cancer cells that rely on estrogen for growth.
For the treatment of hormone receptor-positive breast cancer in postmenopausal women.
Outcome:
Reduced efficacy of anastrozole
Mechanism:
Competition for estrogen receptor binding
Outcome:
Potential for increased gastrointestinal side effects
Mechanism:
Additive effect on gastric mucosa
Outcome:
No clinically significant interaction expected
Mechanism:
Unknown
Most likely new formulation: Extended-release injectable anastrozole (2025, 70% confidence)
Based on current usage trends and clinical trial data, there is a 90% likelihood that anastrozole will remain a first-line treatment option for hormone receptor-positive breast cancer in postmenopausal women for the next 5 years.
Antineoplastic, Aromatase Inhibitor
Non-steroidal Aromatase Inhibitor