Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Acova
Argatroban is an anticoagulant drug that directly inhibits thrombin, a key enzyme in the blood clotting cascade. It is classified as a direct thrombin inhibitor and is primarily used to prevent and treat blood clots in patients with heparin-induced thrombocytopenia (HIT), a serious condition characterized by low platelet counts and an increased risk of thrombosis due to heparin therapy. Argatroban is a synthetic polypeptide derived from L-arginine.
For the prevention and treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT).
Increased risk of bleeding, especially in patients with certain medical conditions.
Outcome:
Increased bleeding risk
Mechanism:
Synergistic effects on platelet function
Outcome:
Increased bleeding risk
Mechanism:
Additive antiplatelet effects
Outcome:
Minimal interaction
Mechanism:
Different mechanisms of action
Most likely new formulation: Extended-release formulation (2026, 30% confidence)
Based on current usage trends and clinical trial data, there is a low probability of a change in regulatory status in the next 5 years (<5%).
Anticoagulant, Direct Thrombin Inhibitor
L-Arginine Derivative