Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Mepron, Malarone, Wellvone
Atovaquone is a synthetic hydroxynaphthoquinone antibiotic-like compound used to treat and prevent Pneumocystis jirovecii pneumonia (PCP) and malaria. It belongs to the class of naphthoquinones and functions by disrupting the electron transport chain in protozoa and fungi, thereby inhibiting their growth and replication.
For preventing and treating Pneumocystis jirovecii pneumonia (PCP) and malaria.
Outcome:
Increased risk of bleeding
Mechanism:
Atovaquone can inhibit the metabolism of warfarin.
Outcome:
Decreased atovaquone absorption
Mechanism:
Reduced bioavailability due to altered pH.
Outcome:
May slightly decrease atovaquone absorption.
Mechanism:
Competition for absorption.
Most likely new formulation: Liposomal atovaquone for improved bioavailability (Year: 2026, 70% confidence)
Based on current usage trends and emerging resistance patterns, there is a 20% likelihood of new regulatory guidelines for atovaquone use in malaria prophylaxis within the next 5 years.
Antiparasitic, Antiprotozoal, Antimalarial
Naphthoquinone