Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Astelin, Astepro, Optivar, Allergodil
Azelastine is an antihistamine that is used to treat allergic rhinitis (hay fever) and allergic conjunctivitis (eye allergy). It works by blocking the action of histamine, a substance in the body that causes allergic symptoms. Azelastine belongs to the class of drugs known as phthalazinones and is available in various forms including nasal sprays, eye drops, and ophthalmic solutions.
For the treatment of allergic rhinitis (hay fever) and allergic conjunctivitis (eye allergy).
Outcome:
Increased drowsiness and impaired coordination.
Mechanism:
Additive CNS depressant effects.
Outcome:
May increase azelastine levels.
Mechanism:
Inhibition of CYP3A4 metabolism.
Outcome:
May slightly decrease the sedative effects of azelastine.
Mechanism:
Caffeine is a CNS stimulant.
Most likely new formulation: sustained-release ocular insert (Year 2026, 60% confidence)
Based on current usage trends and emerging competitors, there is a 70% likelihood of generic azelastine nasal spray maintaining its market share over the next 5 years.
Antihistamine, Phthalazinone
Phthalazinone