Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Colazal, Giazo, Zintasa
Balsalazide is a non-steroidal anti-inflammatory drug (NSAID) specifically designed for the treatment of ulcerative colitis, a form of inflammatory bowel disease (IBD). It belongs to a class of medications called aminosalicylates, which work by reducing inflammation in the lining of the colon. Balsalazide is administered orally and is designed to release the active ingredient, mesalamine (also known as 5-aminosalicylic acid or 5-ASA), primarily in the colon, minimizing systemic exposure and potential side effects.
For the treatment of mild to moderately active ulcerative colitis.
Outcome:
Increased risk of bleeding
Mechanism:
Balsalazide may affect vitamin K absorption, potentially enhancing warfarin's anticoagulant effect.
Outcome:
Reduced digoxin absorption
Mechanism:
Potential interaction through binding in the gut.
Outcome:
Potential for reduced balsalazide absorption
Mechanism:
Possible binding interactions with calcium in dairy.
Most likely new formulation: controlled-release or targeted-delivery systems for improved efficacy and reduced side effects (Year: 2026, 60% confidence)
Based on current usage patterns and emerging research, there is a 70% likelihood of balsalazide maintaining its current FDA approval status for ulcerative colitis over the next 5 years.
Aminosalicylate, Anti-inflammatory
Aminosalicylate