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Brand: Pre-Pen
Benzylpenicilloyl polylysine is a skin test reagent used to diagnose penicillin allergy. It's a synthetic molecule representing the major antigenic determinant of penicillin. When administered intradermally, a positive reaction (wheal and flare) suggests an IgE-mediated allergy to penicillin.
Used for diagnosing penicillin allergy.
Outcome:
False positive skin test
Mechanism:
Cross-reactivity
Outcome:
Reduced skin test reactivity
Mechanism:
H1-receptor blockade
Outcome:
Increased risk of angioedema
Mechanism:
Bradykinin accumulation
Most likely new development: improved diagnostic tests for penicillin allergy utilizing recombinant allergens (Year: 2025, 70% confidence).
Based on historical data, the likelihood of Pre-Pen remaining a standard diagnostic tool for penicillin allergy is high (90%).
Diagnostic Agent
Penicillin Derivative