Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Zebeta, Concor, Bisoprolol-ratiopharm, Emcor
Bisoprolol is a beta-1 selective adrenergic blocking agent, commonly classified as a beta blocker. It is primarily used to treat hypertension (high blood pressure), angina pectoris (chest pain), and heart failure. It works by blocking the effects of adrenaline on the heart, leading to a slower heart rate and reduced force of contraction, which lowers blood pressure and reduces the heart's workload.
For high blood pressure, chest pain (angina), and heart failure.
Outcome:
Reduced bisoprolol levels
Mechanism:
Increased metabolism of bisoprolol
Outcome:
Reduced antihypertensive effect
Mechanism:
NSAIDS inhibit prostaglandin synthesis, which can counteract the vasodilatory effects of bisoprolol.
Outcome:
Slightly reduced bisoprolol absorption
Mechanism:
Altered gastrointestinal pH.
Most likely new formulation: Extended-release combination therapy with other antihypertensives (Year 2025, 70% confidence)
Based on current usage patterns and clinical trial data, there is a low (less than 5%) likelihood of regulatory changes affecting bisoprolol's approval status in the next 5 years.
Beta-blocker, Antihypertensive, Antianginal
Aryloxypropanolamine