Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Pulmicort, Rhinocort, Entocort EC, Uceris, Symbicort
Budesonide is a synthetic glucocorticoid, a type of corticosteroid, with potent anti-inflammatory and immunosuppressive properties. It is used to treat a variety of inflammatory conditions affecting the respiratory system, digestive tract, and skin. Budesonide works by binding to glucocorticoid receptors in the body, which modulates gene expression and reduces the production of inflammatory mediators.
For asthma, COPD, allergic rhinitis, Crohn's disease, and ulcerative colitis.
Outcome:
Increased budesonide levels
Mechanism:
Inhibition of CYP3A4 metabolism
Outcome:
Decreased budesonide levels
Mechanism:
Induction of CYP3A4 metabolism
Outcome:
Slightly decreased budesonide absorption
Mechanism:
Altered stomach pH
Most likely new formulation: Controlled-release inhaled budesonide for once-daily dosing (2025, 75% confidence)
Based on current usage trends and clinical trial data, there is a 90% likelihood of budesonide remaining a first-line treatment for asthma and COPD in the next 5 years.
Corticosteroid, Glucocorticoid
Synthetic Corticosteroid