Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Mentax, Lotrimin Ultra
Butenafine is a synthetic antifungal medication belonging to the benzylamine class. It works by inhibiting squalene epoxidase, an enzyme crucial for fungal cell membrane synthesis. This disruption leads to squalene accumulation and ergosterol deficiency, ultimately causing fungal cell death. Butenafine is effective against a broad range of dermatophytes, yeasts, and molds, making it suitable for treating various fungal skin infections.
For the treatment of athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis).
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Potential for increased skin irritation
Mechanism:
Not fully understood
Most likely new formulation: Topical spray (2025, 60% confidence)
Based on current usage trends and clinical trial data, there is a low probability ( <5%) of any major regulatory changes in the next 5 years.
Antifungal
Benzylamine