Medicines
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Discover all available medicines and treatments
Brand: Vocabria, Apretude
Cabotegravir is an integrase strand transfer inhibitor (INSTI) used for the treatment and prevention of HIV-1 infection. It works by blocking the enzyme integrase, which HIV needs to integrate its genetic material into the DNA of human cells. This prevents the virus from replicating and spreading. Cabotegravir is available as both an oral tablet and a long-acting injectable formulation.
Cabotegravir is used for the treatment and prevention of HIV-1 infection in adults.
Outcome:
Decreased cabotegravir levels
Mechanism:
Induction of drug-metabolizing enzymes
Outcome:
Potential drug interaction
Mechanism:
Both are INSTIs
Outcome:
Potential for reduced cabotegravir absorption
Mechanism:
Chelation
Most likely new formulation: extended-release implant (2025, 75% confidence)
Based on current clinical trial data and increasing usage trends, there is a 90% likelihood of cabotegravir maintaining its approved status for HIV treatment and prevention.
Antiretroviral, Integrase Inhibitor
INSTI (Integrase Strand Transfer Inhibitor)