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Brand: Atacand, Blopress
Candesartan is an angiotensin II receptor blocker (ARB) used primarily to treat high blood pressure (hypertension) and heart failure. It works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, leading to increased blood pressure. Candesartan helps relax and widen blood vessels, making it easier for the heart to pump blood and lowering blood pressure. It's often prescribed when other blood pressure medications, like ACE inhibitors, are not tolerated due to side effects like a dry cough.
For treating high blood pressure (hypertension) and heart failure.
Outcome:
Hyperkalemia
Mechanism:
Reduced potassium excretion
Outcome:
Additive hypotensive effect
Mechanism:
Synergistic effects on blood pressure
Outcome:
Reduced absorption of candesartan
Mechanism:
Chelation/binding
Most likely new formulation: combination therapy with a thiazide diuretic (2025, 75% confidence).
Based on current usage trends and clinical trial data, there is a 90% likelihood that candesartan will maintain its approved status for hypertension and heart failure.
Angiotensin II Receptor Blocker (ARB)
Tetrazole