Medicines
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Discover all available medicines and treatments
Brand: Zostrix, Capzasin-P, Qutenza
Capsaicin is an active component of chili peppers, which are plants belonging to the genus Capsicum. It is an irritant for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact. Capsaicin and several related compounds are called capsaicinoids and are produced as secondary metabolites by chili peppers, probably as deterrents against certain mammals and fungi. Pure capsaicin is a hydrophobic, colorless, odorless, crystalline to waxy compound.
Used topically for temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, strains, sprains, and bruises; also used for temporary relief of muscle or joint pain associated with conditions such as osteoarthritis, rheumatoid arthritis, and psoriatic arthritis.
Outcome:
May exacerbate burning sensation.
Mechanism:
Potential for increased skin sensitivity.
Outcome:
May increase absorption of other topical medications.
Mechanism:
Increased skin permeability.
Outcome:
May increase cough related to ACE inhibitors.
Mechanism:
Unknown
Most likely new formulation: Topical patch with sustained-release capsaicin for chronic pain (Year: 2026, 80% confidence)
Based on current usage trends and clinical trial data, there is a 70% likelihood of expanded indications for capsaicin in neuropathic pain management within the next 5 years.
Analgesic, Counterirritant
Capsaicinoid