Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Geocillin, Pyopen
Carbenicillin is a semi-synthetic penicillin antibiotic belonging to the carboxypenicillin subclass. It is primarily used to treat infections caused by gram-negative bacteria, including Pseudomonas aeruginosa. It works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death.
For treating infections caused by gram-negative bacteria, particularly Pseudomonas aeruginosa.
Outcome:
Increased carbenicillin levels
Mechanism:
Reduced renal excretion of carbenicillin
Outcome:
Increased risk of bleeding
Mechanism:
Additive effects on platelet function
Outcome:
Reduced carbenicillin absorption
Mechanism:
Chelation or binding of carbenicillin in the GI tract
Most likely new formulation: Extended-release injectable formulation (Year 2025, 30% confidence)
Based on declining usage and the availability of newer, broader-spectrum antibiotics, there is a 20% likelihood of carbenicillin being withdrawn from some markets in the next 10 years.
Antibiotic, Beta-lactam, Carboxypenicillin
Carboxypenicillin