Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Paraplatin
Carboplatin is a platinum-based chemotherapy drug used to treat various types of cancer. It belongs to the class of alkylating agents and works by interfering with DNA replication, ultimately leading to cancer cell death. It is often used in combination with other chemotherapy drugs.
Used to treat various types of cancer, including ovarian, lung, head and neck, and testicular cancers.
Myelosuppression, including fatal cases, has occurred. Monitor blood counts frequently. Severe or fatal allergic reactions have been reported, some following the first dose. Anaphylactic-like reactions have occurred within minutes of starting carboplatin infusion. Appropriate resuscitation equipment should be available. Renal toxicity has been reported and may be cumulative. Monitor renal function prior to and during therapy. Ototoxicity has been reported. Monitor hearing prior to and during therapy. Embryotoxic and teratogenic in animals; avoid use in pregnancy.
Outcome:
Increased risk of nephrotoxicity and ototoxicity
Mechanism:
Additive toxic effects on the kidneys and inner ear
Outcome:
Increased risk of bleeding
Mechanism:
Carboplatin can cause thrombocytopenia, and NSAIDs can inhibit platelet function.
Outcome:
May mask allergic reactions to carboplatin
Mechanism:
Suppression of allergic symptoms
Most likely new formulation: Nanoparticle-based drug delivery system for improved efficacy and reduced side effects (Year 2026, 70% confidence).
Based on current usage trends and ongoing clinical trials, carboplatin is expected to maintain its status as a key chemotherapeutic agent for various cancers, with a 90% likelihood of remaining on major formularies for the next 5 years.
Antineoplastic, Alkylating Agent, Platinum Analog
Platinum Coordination Complex