Medicines
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Discover all available medicines and treatments
Brand: Hemabate
Carboprost tromethamine is a synthetic prostaglandin F2α analog used to induce abortion and control postpartum hemorrhage. It acts by stimulating uterine contractions, promoting the expulsion of uterine contents. Carboprost is classified as an oxytocic agent.
Used for abortion and control of postpartum hemorrhage.
Outcome:
Increased risk of uterine rupture
Mechanism:
Synergistic effect on uterine contractions
Outcome:
Reduced efficacy of carboprost
Mechanism:
Inhibition of prostaglandin synthesis
Outcome:
Potential decreased absorption of carboprost
Mechanism:
Changes in gastric pH
Most likely new formulation: Controlled-release implant (2028, 30% confidence)
Based on current usage trends and safety profile, the likelihood of regulatory changes in the next 5 years is low (<5%).
Prostaglandin, Oxytocic
Prostaglandin F2α analog