Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Fortaz, Tazicef, Ceftaz, Glazidim
Ceftazidime is a third-generation cephalosporin antibiotic used to treat a wide variety of bacterial infections. It works by inhibiting bacterial cell wall synthesis, leading to cell death. It is effective against many gram-negative bacteria, including Pseudomonas aeruginosa, and some gram-positive bacteria. Ceftazidime is available as an intravenous and intramuscular injection.
For the treatment of serious bacterial infections, including lower respiratory tract infections, skin and soft tissue infections, urinary tract infections, meningitis, and septicemia.
Outcome:
Antagonistic effect, reducing the effectiveness of both drugs.
Mechanism:
Competition for binding sites.
Outcome:
Disulfiram-like reaction (rare).
Mechanism:
Inhibition of acetaldehyde dehydrogenase.
Outcome:
Reduced absorption of ceftazidime.
Mechanism:
Chelation or binding in the GI tract.
Most likely new formulation: Ceftazidime-avibactam combination therapy for resistant infections (2025, 80% confidence)
Based on increasing resistance patterns, there is a 20% likelihood of new guidelines restricting ceftazidime use in uncomplicated infections within the next 5 years.
Cephalosporin, Beta-lactam Antibiotic
Cephalosporin