Medicines
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Discover all available medicines and treatments
Brand: Cetrotide
Cetrorelix acetate is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonist activity. It competes with natural GnRH for binding to pituitary GnRH receptors, thereby rapidly suppressing the secretion of gonadotropins, luteinizing hormone (LH), and follicle-stimulating hormone (FSH). This action prevents premature LH surges in women undergoing controlled ovarian stimulation for assisted reproductive technologies (ART).
Used to prevent premature ovulation in women undergoing controlled ovarian hyperstimulation for assisted reproductive technologies.
Outcome:
Reduced efficacy of cetrorelix
Mechanism:
Competitive binding at GnRH receptors
Outcome:
Potential alterations in drug metabolism
Mechanism:
Cetrorelix may affect CYP450 enzyme activity
Outcome:
Minimal effect on drug clearance
Mechanism:
Renal clearance is not a primary route of elimination
Most likely new formulation: Sustained-release cetrorelix implant (Year 2026, 75% confidence)
Based on current usage trends and clinical trial data, there is a 90% likelihood that cetrorelix will maintain its current regulatory status for assisted reproductive technologies.
Gonadotropin-Releasing Hormone Antagonist
Decapeptide