Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Thorazine, Largactil
Chlorpromazine is a first-generation antipsychotic medication primarily used to treat psychotic disorders such as schizophrenia. It belongs to the phenothiazine class of drugs and works by blocking dopamine receptors in the brain. It can also be used to manage mania, nausea and vomiting, and anxiety before surgery.
For the treatment of schizophrenia, mania, nausea and vomiting, and pre-operative anxiety.
Increased mortality in elderly patients with dementia-related psychosis.
Outcome:
Increased sedation and drowsiness
Mechanism:
Additive CNS depression
Outcome:
Reduced absorption of chlorpromazine
Mechanism:
Chelation
Outcome:
Slightly decreased effectiveness of chlorpromazine
Mechanism:
Caffeine's stimulant effects
Most likely new formulation: Extended-release injectable (2025, 70% confidence)
Based on usage patterns and adverse event reports, there is a 1% likelihood of new black box warnings related to metabolic effects within the next 5 years.
Antipsychotic, Phenothiazine
Phenothiazine