Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Catapres, Kapvay, Dixarit, Jenloga, Clophelin
Clonidine is a centrally acting alpha-2 adrenergic agonist that reduces sympathetic nerve activity, thereby decreasing peripheral vascular resistance, renal vascular resistance, heart rate, and blood pressure. It is used to treat hypertension, attention deficit hyperactivity disorder (ADHD), and certain withdrawal symptoms. Clonidine exists in immediate-release and extended-release forms.
For treating hypertension, ADHD, and certain withdrawal symptoms.
Outcome:
Increased risk of hypertension
Mechanism:
Additive effects on blood pressure
Outcome:
Bradycardia
Mechanism:
Additive effects on heart rate
Outcome:
Reduced antihypertensive effect
Mechanism:
Stimulant effects
Most likely new formulation: Transdermal patch with improved bioavailability (2025, 80% confidence)
Based on current usage trends and clinical trial data, there is a 70% likelihood of clonidine remaining a first-line treatment for hypertension in the next 5 years.
Antihypertensive, Centrally Acting Alpha-2 Adrenergic Agonist
Imidazoline