Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Flexeril, Amrix, Fexmid
Cyclobenzaprine is a centrally acting skeletal muscle relaxant primarily used for short-term relief of muscle spasms associated with acute, painful musculoskeletal conditions. It is structurally similar to tricyclic antidepressants and is believed to act within the brainstem to reduce tonic somatic motor activity, although its precise mechanism of action remains unclear. Cyclobenzaprine is typically prescribed for use in conjunction with rest and physical therapy.
For short-term relief of muscle spasm associated with acute, painful musculoskeletal conditions.
Outcome:
Serotonin syndrome
Mechanism:
Increased serotonin levels
Outcome:
Decreased antihypertensive effect
Mechanism:
Inhibition of guanethidine uptake
Outcome:
Increased risk of bleeding
Mechanism:
Both drugs can affect platelet function
Most likely new formulation: Extended-release cyclobenzaprine with improved tolerability (Year 2026, 70% confidence)
Based on current usage trends and safety profile, cyclobenzaprine's regulatory status is predicted to remain stable with a 95% likelihood of continued approval for the next 5 years.
Skeletal Muscle Relaxant, Centrally Acting
Tricyclic Compound