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Brand: Cyclogyl, Minims Cyclopentolate Hydrochloride, Ak-Pentolate, Ocu-Pentolate
Cyclopentolate is an anticholinergic medication primarily used to dilate the pupil (mydriasis) and paralyze the ciliary muscle (cycloplegia) of the eye. It belongs to the class of muscarinic antagonists and works by blocking the action of acetylcholine, a neurotransmitter that controls muscle contraction in the eye. This allows for easier examination of the interior structures of the eye and is particularly useful in ophthalmic procedures such as refraction and fundus examination.
For dilating the pupil and paralyzing the ciliary muscle during eye examinations.
Outcome:
Increased anticholinergic effects
Mechanism:
Additive anticholinergic activity
Outcome:
Increased anticholinergic effects
Mechanism:
Additive anticholinergic activity
Outcome:
Potential for decreased nitrate effect
Mechanism:
Unknown
Most likely new formulation: sustained-release ocular insert (Year 2026, 70% confidence)
Based on historical usage and safety data, cyclopentolate is predicted to maintain its current regulatory status with a 95% likelihood.
Anticholinergic, Mydriatic, Cycloplegic
Tertiary amine