Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Aczone, Avlosulfon
Dapsone is an antibiotic primarily used to treat leprosy (Hansen's disease) and certain skin conditions. It belongs to the sulfone class of antibiotics and works by inhibiting bacterial synthesis of dihydrofolic acid, essential for bacterial growth. It's also used in combination with other drugs for pneumocystis pneumonia and certain autoimmune diseases like dermatitis herpetiformis.
Used to treat leprosy, certain skin conditions, pneumocystis pneumonia, and some autoimmune diseases.
Outcome:
Increased risk of hemolytic anemia
Mechanism:
Both drugs can cause oxidative stress on red blood cells.
Outcome:
Altered anticoagulant effect
Mechanism:
Competition for plasma protein binding.
Outcome:
Decreased dapsone absorption
Mechanism:
Changes in gastric pH.
Most likely new formulation: Liposomal dapsone for improved bioavailability and reduced toxicity (Year: 2026, 60% confidence)
Based on current usage trends and emerging resistance patterns, there is a 15% likelihood of new guidelines for dapsone use in leprosy treatment within the next 5 years.
Antibiotic, Anti-inflammatory
Sulfone