Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Pristiq, Khedezla
Desvenlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant used to treat major depressive disorder (MDD). It works by increasing the levels of serotonin and norepinephrine, two neurotransmitters in the brain that are believed to play a key role in regulating mood.
For the treatment of major depressive disorder.
Suicidal thoughts and behaviors in children, adolescents, and young adults taking antidepressants.
Outcome:
Serotonin syndrome
Mechanism:
Increased serotonin levels
Outcome:
Increased sedation
Mechanism:
Additive CNS depressant effects
Outcome:
Decreased desvenlafaxine absorption
Mechanism:
Altered gastric pH
Most likely new formulation: Extended-release formulation (Year 2025, 70% confidence)
Based on current usage trends and clinical trial data, there is a low likelihood of regulatory changes in the near future (less than 5%).
Antidepressant, SNRI
Cyclohexanol