Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Precedex, Dexdor
Dexmedetomidine is a selective alpha-2 adrenergic agonist used for sedation and analgesia in various clinical settings. It provides a unique form of sedation characterized by arousability and minimal respiratory depression compared to other sedatives. It's often utilized in intensive care units (ICUs) for short-term sedation of intubated and mechanically ventilated patients, as well as during procedural sedation.
For sedation and analgesia in intensive care and procedural settings.
Outcome:
Increased sedation, respiratory depression
Mechanism:
Additive CNS depressant effects
Outcome:
Increased risk of bradycardia and hypotension
Mechanism:
Additive effects on heart rate and blood pressure
Outcome:
Increased sedation
Mechanism:
Additive CNS depressant effects
Most likely new formulation: Extended-release oral formulation (2025, 60% confidence)
Based on increasing ICU usage and positive clinical trial data, there is a 70% likelihood of expanded indications for dexmedetomidine in the next 5 years.
Alpha-2 adrenergic agonist, Sedative, Analgesic
Imidazole derivative