Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Psorcon, Maxiflor, Florone, Diacetate, ApexiCon E
Diflorasone diacetate is a potent topical corticosteroid used to treat inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. It belongs to the class of corticosteroids, specifically Group I (super-high potency). Diflorasone works by binding to glucocorticoid receptors, which leads to the suppression of inflammatory mediators and the reduction of vascular permeability.
For the relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Outcome:
Increased systemic absorption of diflorasone
Mechanism:
Inhibition of diflorasone metabolism
Outcome:
Increased risk of gastrointestinal bleeding
Mechanism:
Additive effects on gastric mucosa
Outcome:
May decrease absorption of diflorasone
Mechanism:
Altered pH in the gastrointestinal tract
Most likely new formulation: A combination product with a non-steroidal anti-inflammatory drug (2026, 30% confidence).
Based on current usage trends and clinical trial data, there is a low probability ( <5%) of any major regulatory changes for diflorasone in the next 2 years.
Corticosteroid, Group I (Super-High Potency)
Difluorinated Corticosteroid