Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Propine
Dipivefrin is a prodrug of epinephrine used to reduce elevated intraocular pressure in open-angle glaucoma. It's classified as an adrenergic agonist and works by increasing the outflow of aqueous humor from the eye. It's often preferred over epinephrine due to its improved corneal penetration and reduced incidence of side effects.
For reducing elevated intraocular pressure in open-angle glaucoma.
Outcome:
Increased risk of cardiovascular side effects.
Mechanism:
Additive adrenergic effects.
Outcome:
Reduced efficacy of both drugs.
Mechanism:
Potential antagonistic effects on intraocular pressure.
Outcome:
Mild dryness of the eyes.
Mechanism:
Additive anticholinergic effects.
Most likely new formulation: sustained-release formulation (Year: 2026, 60% confidence)
Based on current usage patterns and clinical trial data, there is a low ( <5%) likelihood of any major regulatory changes to dipivefrin's status in the next 5 years.
Antiglaucoma Agent, Adrenergic Agonist
Dihydropyridine