Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Norpace, Rythmodan, Dirythmin
Disopyramide is an antiarrhythmic medication used to treat certain types of irregular heartbeats (arrhythmias), specifically ventricular arrhythmias. It belongs to the Class IA antiarrhythmic drug class and works by blocking sodium channels in the heart, slowing the conduction of electrical impulses and stabilizing the heart rhythm.
Used to treat certain types of irregular heartbeats (ventricular arrhythmias).
Disopyramide can worsen heart failure symptoms and increase mortality in patients with pre-existing heart failure.
Outcome:
Increased digoxin levels, leading to toxicity
Mechanism:
Disopyramide can reduce the clearance of digoxin.
Outcome:
Decreased disopyramide levels
Mechanism:
Rifampin induces the metabolism of disopyramide.
Outcome:
Decreased disopyramide absorption
Mechanism:
Antacids can bind to disopyramide.
Most likely new formulation: Extended-release formulation to improve patient compliance (Year: 2026, 30% confidence)
Based on current usage trends and ongoing clinical trials, there is a low (5%) likelihood of any major regulatory changes for disopyramide in the next 2 years.
Antiarrhythmic, Class IA
Pyrrolidinamide