Medicines
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Discover all available medicines and treatments
Brand: Dobutrex
Dobutamine is a synthetic catecholamine used in the short-term treatment of heart failure and cardiogenic shock. It acts primarily on beta-1 adrenergic receptors in the heart, increasing myocardial contractility and cardiac output without significantly affecting heart rate or peripheral vascular resistance. Dobutamine is administered intravenously and is typically used in hospital settings under close monitoring.
For short-term treatment of heart failure and cardiogenic shock.
Outcome:
Reduced inotropic effect of dobutamine.
Mechanism:
Beta-blockers antagonize the beta-1 adrenergic receptor stimulation by dobutamine.
Outcome:
Hypokalemia.
Mechanism:
Enhanced potassium loss.
Outcome:
Reduced dobutamine absorption.
Mechanism:
Altered gastric pH.
Most likely new formulation: Controlled-release formulation (Year: 2026, 30% confidence)
Based on current usage trends and clinical trial data, there is a low (5%) likelihood of any major regulatory changes in the next 2 years.
Inotropic Agent, Sympathomimetic
Catecholamine