Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Trusopt, Cosopt
Dorzolamide is a carbonic anhydrase inhibitor used to lower intraocular pressure in the treatment of open-angle glaucoma and ocular hypertension. It works by decreasing the production of aqueous humor, the fluid that fills the front part of the eye. Dorzolamide is typically administered as eye drops.
Used to lower intraocular pressure in open-angle glaucoma and ocular hypertension.
Outcome:
Additive systemic effects
Mechanism:
Similar mechanism of action
Outcome:
Antagonistic effects on pupil size
Mechanism:
Dorzolamide can cause miosis, while anticholinergics cause mydriasis.
Outcome:
Dilution of dorzolamide
Mechanism:
Physical dilution of the drug
Most likely new formulation: Sustained-release implant (Year: 2028, 60% confidence)
Based on current usage trends and clinical trial data, there is a low likelihood of any major regulatory changes for dorzolamide in the next 5 years (less than 10% chance).
Carbonic Anhydrase Inhibitor, Antiglaucoma Agent
Sulfonamide