Medicines
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Discover all available medicines and treatments
Brand: Dopram
Doxapram is a central nervous system stimulant that primarily acts on the respiratory centers in the brainstem. It is used to stimulate breathing in certain clinical situations, such as post-anesthesia respiratory depression, drug-induced respiratory depression, and in patients with chronic obstructive pulmonary disease (COPD) who have acute hypercapnic respiratory failure. Doxapram increases the depth and rate of respiration.
Stimulates breathing in cases of respiratory depression or failure.
Outcome:
Hypertensive crisis
Mechanism:
Increased catecholamine release
Outcome:
Reduced bronchodilation
Mechanism:
Antagonistic effects on bronchial smooth muscle
Outcome:
Slightly decreased doxapram absorption
Mechanism:
Altered gastric pH
Most likely new formulation: Controlled-release formulation for improved patient compliance (Year 2026, 30% confidence)
Based on historical usage patterns and current clinical trials, there is a low (5%) likelihood of any major regulatory changes to doxapram's status in the next 5 years.
Respiratory Stimulant
Piperidine Derivative