Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Yasmin, Yaz, Beyaz, Ocella, Gianvi, Loryna, Syeda, Nikki, Safyral
Drospirenone is a synthetic progestin used in combination with ethinyl estradiol in oral contraceptives. It belongs to the class of spironolactone analogues and exhibits antimineralocorticoid and antiandrogenic properties, making it beneficial for managing acne and premenstrual symptoms. It is also unique among progestins in not causing weight gain and having a positive effect on mood, thanks to its mild diuretic effect.
For contraception, acne treatment, and premenstrual syndrome relief.
Increased risk of venous thromboembolism compared to combined oral contraceptives containing levonorgestrel or some other progestins.
Outcome:
Hyperkalemia
Mechanism:
Additive potassium retention
Outcome:
Reduced contraceptive efficacy
Mechanism:
Altered gut flora
Outcome:
Increased caffeine levels
Mechanism:
Inhibition of metabolism
Most likely new formulation: Extended-cycle drospirenone-containing contraceptive pills (2025, 75% confidence).
Based on current usage trends and safety profile, there is a 90% likelihood that drospirenone will remain a widely prescribed contraceptive option for the next 5 years.
Progestin, Antimineralocorticoid, Antiandrogen
Spironolactone Analogue