Medicines
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Discover all available medicines and treatments
Brand: Tensilon, Enlon
Edrophonium is a short-acting cholinesterase inhibitor used primarily for the diagnosis of myasthenia gravis. It works by temporarily increasing the levels of acetylcholine, a neurotransmitter, at the neuromuscular junction. This can briefly improve muscle strength in individuals with myasthenia gravis. It is also used to differentiate between myasthenic crisis and cholinergic crisis, and occasionally to reverse the effects of nondepolarizing neuromuscular blocking agents.
Used for diagnosing myasthenia gravis, differentiating myasthenic and cholinergic crises, and reversing nondepolarizing neuromuscular blockade.
Outcome:
Prolonged neuromuscular blockade
Mechanism:
Edrophonium may enhance the effects of succinylcholine.
Outcome:
Increased bradycardia
Mechanism:
Additive negative chronotropic effects.
Outcome:
Decreased edrophonium efficacy
Mechanism:
Theophylline can antagonize cholinergic effects.
Most likely new formulation: Sustained-release edrophonium for improved myasthenia gravis management (Year: 2028, 30% confidence)
Based on current usage trends and emerging diagnostic methods, there is a 15% likelihood of a decrease in edrophonium prescriptions over the next 5 years.
Cholinesterase Inhibitor, Diagnostic Agent
Alcohol