Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Ovestin, Ortho-Gynest, Gynest, Synapause, Blissy
Estriol is a naturally occurring weak estrogen primarily produced during pregnancy. It's one of the three main estrogens produced by the human body, along with estrone and estradiol. It's used in hormone replacement therapy (HRT), particularly in menopausal women, to alleviate symptoms like vaginal dryness and atrophy. Compared to other estrogens, estriol has a shorter duration of action and a lower binding affinity to estrogen receptors, making it considered a "weaker" estrogen.
Used primarily for the treatment of menopausal symptoms like vaginal dryness and atrophy.
Outcome:
Increased bleeding risk
Mechanism:
Estriol can alter the metabolism of warfarin.
Outcome:
May slightly increase estriol levels
Mechanism:
Competition for protein binding.
Outcome:
Generally considered safe to use together
Mechanism:
Minimal interaction expected.
Most likely new formulation: Transdermal patch for sustained release (Year: 2026, 60% confidence)
Based on current usage trends and ongoing research, there is a 70% likelihood of estriol remaining a first-line treatment for vaginal atrophy in the next 5 years.
Estrogen, Steroid Hormone
Steroid