Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Aromasin
Exemestane is an irreversible steroidal aromatase inhibitor used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It works by blocking the enzyme aromatase, which is responsible for converting androgens to estrogens in peripheral tissues. This reduces estrogen levels, inhibiting the growth of estrogen-dependent breast cancer cells.
For the treatment of hormone receptor-positive breast cancer in postmenopausal women.
Outcome:
Increased risk of bleeding
Mechanism:
Exemestane can inhibit CYP2C9, which metabolizes warfarin.
Outcome:
Potential for decreased exemestane efficacy
Mechanism:
Competition for binding sites.
Outcome:
Generally safe to use concomitantly
Mechanism:
No significant interaction expected.
Most likely new formulation: extended-release formulation (Year: 2026, 60% confidence)
Based on current usage trends and clinical trial data, there is a low likelihood of significant regulatory changes in the next 5 years.
Antineoplastic, Aromatase Inhibitor
Steroid