Medicines
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Discover all available medicines and treatments
Brand: Fampyra, Ampyra
Fampyra, also known by its generic name fampridine, is a potassium channel blocker indicated to improve walking in adults with multiple sclerosis (MS). It works by blocking potassium channels on damaged nerve fibers, which helps to improve nerve conduction and muscle strength. It's classified as a symptomatic treatment, meaning it addresses the symptoms of MS, specifically walking difficulties, rather than the underlying disease process.
To improve walking in adults with multiple sclerosis.
Outcome:
Increased risk of seizures
Mechanism:
Both drugs can lower the seizure threshold.
Outcome:
Increased fampridine levels
Mechanism:
Cimetidine inhibits fampridine metabolism.
Outcome:
Decreased fampridine absorption
Mechanism:
Altered gastric pH.
Most likely new formulation: extended-release formulation (Year: 2026, 70% confidence)
Based on current usage patterns and clinical trial data, there is a low (less than 10%) likelihood of significant regulatory changes in the near future.
Potassium Channel Blocker
4-Aminopyridine