Medicines
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Discover all available medicines and treatments
Brand: Corlopam
Fenoldopam is a selective dopamine-1 receptor agonist used in the short-term treatment of severe hypertension. It works by activating dopamine-1 receptors in the renal vasculature, leading to vasodilation and increased renal blood flow, thereby promoting natriuresis and diuresis. It's classified as a vasodilator and is typically administered intravenously.
For the short-term treatment of severe hypertension.
Outcome:
Reduced antihypertensive effect of fenoldopam.
Mechanism:
Pharmacodynamic antagonism.
Outcome:
Reduced antihypertensive effect.
Mechanism:
NSAIDs can impair renal function and reduce fenoldopam's effectiveness.
Outcome:
No clinically significant interaction expected.
Mechanism:
Different mechanisms of action.
Most likely new formulation: Controlled-release formulation for longer-term hypertension management (Year: 2028, 30% confidence)
Based on current usage trends and clinical trial data, there is a low probability ( <5%) of a change to fenoldopam's regulatory status in the next 5 years.
Vasodilator, Dopamine-1 Receptor Agonist
Benzazepine