Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Diflucan, Canesten Oral Capsule
Fluconazole is a triazole antifungal medication used to treat a variety of fungal infections. It works by inhibiting the synthesis of ergosterol, a crucial component of fungal cell membranes. This disruption leads to increased membrane permeability and ultimately fungal cell death. Fluconazole is effective against a broad range of fungi, including Candida species, Cryptococcus neoformans, and some Aspergillus species.
For the treatment of vaginal yeast infections, oral thrush, and other fungal infections.
Outcome:
Increased risk of serious cardiac arrhythmias
Mechanism:
Fluconazole inhibits the metabolism of cisapride, leading to elevated cisapride levels.
Outcome:
Increased risk of bleeding
Mechanism:
Fluconazole can enhance the anticoagulant effect of warfarin.
Outcome:
Reduced fluconazole absorption
Mechanism:
Antacids can interfere with fluconazole absorption.
Most likely new formulation: A combination therapy with another antifungal to combat emerging resistance (Year: 2026, 70% confidence)
Based on current usage trends and emerging resistance patterns, there is a 15% likelihood of new restrictions on fluconazole use for certain indications within the next 5 years.
Triazole Antifungal
Triazole