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Discover all available medicines and treatments
Brand: Florinef, Astonin-H
Fludrocortisone is a synthetic mineralocorticoid used primarily as replacement therapy for adrenal insufficiency. It acts by mimicking the effects of aldosterone, a hormone produced by the adrenal glands that regulates salt and water balance in the body. Fludrocortisone is classified as a corticosteroid and is available in oral tablet form.
For the treatment of Addison's disease, salt-losing adrenogenital syndrome, and orthostatic hypotension.
Outcome:
Severe hypokalemia
Mechanism:
Additive potassium loss
Outcome:
Hypokalemia
Mechanism:
Additive potassium loss
Outcome:
Decreased fludrocortisone absorption
Mechanism:
Binding interaction
Most likely new formulation: sustained-release oral formulation (2026, 30% confidence)
Based on current usage patterns and clinical trial data, there is a low ( <5%) likelihood of any major regulatory changes for fludrocortisone in the next 5 years.
Mineralocorticoid, Corticosteroid
Steroid