Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Prozac, Sarafem, Fontex, Fluctin, Ladose, Prodep, Deprex, Foxetin, Adofen
Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant primarily used to treat major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa, and panic disorder. It works by increasing the levels of serotonin, a neurotransmitter in the brain that helps regulate mood, sleep, and appetite.
For major depressive disorder, obsessive-compulsive disorder, bulimia nervosa, and panic disorder.
Increased risk of suicidal thinking and behavior in children, adolescents, and young adults (18-24 years of age) taking antidepressants for major depressive disorder and other psychiatric disorders.
Outcome:
Serotonin syndrome
Mechanism:
Increased serotonin levels
Outcome:
Increased bleeding risk
Mechanism:
Pharmacodynamic interaction
Outcome:
Reduced fluoxetine efficacy
Mechanism:
Pharmacokinetic interaction
Most likely new formulation: Extended-release combination with a second antidepressant (Year 2025, 70% confidence)
Based on usage trends and clinical trial data, there is a 90% likelihood that fluoxetine will remain a first-line treatment for depression for the next 5 years.
Antidepressant, SSRI
Selective Serotonin Reuptake Inhibitor (SSRI)