Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Lescol, Lescol XL
Fluvastatin is a synthetic statin medication used to lower cholesterol levels in the blood. It belongs to the class of HMG-CoA reductase inhibitors, which work by inhibiting an enzyme crucial for cholesterol synthesis in the liver. This leads to a reduction in total cholesterol, LDL ("bad") cholesterol, and triglycerides, while also modestly increasing HDL ("good") cholesterol. Fluvastatin is typically prescribed for individuals with high cholesterol or those at risk of cardiovascular disease.
Used to lower cholesterol levels and reduce the risk of cardiovascular disease.
Outcome:
Increased risk of myopathy and rhabdomyolysis
Mechanism:
Inhibition of fluvastatin metabolism
Outcome:
Increased risk of myopathy
Mechanism:
Additive effects on muscle toxicity
Outcome:
Slightly increased risk of bleeding
Mechanism:
Additive effects on platelet function
Most likely new formulation: Combination therapy with other cholesterol-lowering agents (Year: 2025, 70% confidence)
Based on current usage trends and clinical trial data, there is a low likelihood of any major regulatory changes for fluvastatin in the next 2 years (less than 5% probability).
HMG-CoA Reductase Inhibitor, Statin
Fully synthetic 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor