Medicines
Discover all available medicines and treatments
Discover all available medicines and treatments
Brand: Neurontin, Gralise, Horizant
Gabapentin is an anticonvulsant medication structurally related to the neurotransmitter gamma-aminobutyric acid (GABA), although it does not bind to GABA receptors. It is used primarily to treat neuropathic pain and seizures, as well as for off-label uses like restless legs syndrome and anxiety disorders. It is available as a generic and under various brand names.
For neuropathic pain, seizures, and off-label uses such as restless legs syndrome and anxiety disorders.
Suicidal thoughts or actions
Outcome:
Increased central nervous system depression
Mechanism:
Additive CNS depressant effects
Outcome:
Increased gabapentin levels
Mechanism:
Inhibition of renal excretion
Outcome:
May slightly delay absorption
Mechanism:
Delayed gastric emptying
Most likely new formulation: Extended-release gabapentin for fibromyalgia (Year: 2026, 65% confidence)
Based on usage patterns and emerging research, there is a 70% likelihood of new gabapentinoid formulations for specific neuropathic pain conditions being approved within the next 5 years.
Anticonvulsant, GABA Analog
Cyclohexyl GABA analog